Application Guide - QIAxcel Advanced

QIAxcel Advanced Application Guide 10/2016 63 Visit www.qiagen.com/HLA-typing and find out how automated gel electrophoresis can benefit your lab! Trademarks: QIAGEN® , QIAxcel® , Sample to Insight® , ScreenGel™ (QIAGEN Group). Registered names, trademarks, etc. used in this document, even when not specifically marked as such, are not to be considered unprotected by law. Ordering www.qiagen.com/shop Technical Support support.qiagen.com Website www.qiagen.com Ordering Information Product Contents Cat. no. QIAxcel Advanced System Capillary electrophoresis device, including computer, and QIAxcel ScreenGel™ Software; 1-year warranty on parts and labor 9001941 QIAxcel DNA Fast Analysis Kit (3000) QIAxcel DNA Fast Analysis Cartridge, Buffers, Mineral Oil, QX Intensity Calibration Marker, QX DNA Size Marker 50 bp – 1.5 kb, QX Alignment Marker 15 bp/3 kb, 12-Tube Strips 929008 For SSP-based HLA tissue typing applications, the above products can be directly ordered from Olerup SSP (www.olerup-ssp.com). For this application, these products should be exclusively ordered from Olerup SSP in the following countries: Australia, Belgium, Brazil, Canada, China, Denmark, Finland, France, Germany, Italy, Japan, Korea, Luxembourg, Malaysia, Mexico, Netherlands, Norway, Singapore, Sweden, United Kingdom, and USA. In all other countries, the products can be ordered from Olerup SSP as well as from QIAGEN or QIAGEN’s distributors. For other applications of HLA typing, the products should be ordered from QIAGEN or QIAGEN’s distributors. For up-to-date licensing information and product-specific disclaimers, see the respective QIAGEN kit handbook or user manual. QIAGEN kit handbooks and user manuals are available at www.qiagen.com or can be requested from QIAGEN Technical Services or your local distributor. References 1. Marsh, S.G.E., Parham, P., and Barber, L.D. (2000) HLA FactsBook. San Diego: Academic Press. 2. Gerlach, J.A. (2002) Human lymphocyte antigen molecular typing: how to identify the 1250+ alleles out there. Arch. Pathol. Lab. Med. 126:281. 3. Weyand, C.M., and Goronzy, J. (2000) Association of MHC and rheumatoid arthritis: HLA polymorphisms in phenotypic variants of rheumatoid arthritis. Arthritis Res. 2:212. 4. Klein, J., and Sato, A. (2000) The HLA system. Second of two parts. N. Engl. J. Med. 343:782. 5. Haan, K.M., Kwok, W.W., Longnecker, R., and Speck, P. (2000) Epstein-Barr virus entry utilizing HLA-DP or HLA-DQ as a coreceptor. J. Virol. 74:2451. 6. Reveille, J.D., (2006) Major histocompatibility genes and ankylosing spondylitis. Best Pract. Res. Clin. Rheumatol. 20:601. 7. Amital, H., et al. (2008) Role of infectious agents in systemic rheumatic diseases. Clin. Exp. Rheumatol. 26:S27. 8. Chiu, H.K., and Palmer, J.P. (2004). Autoimmune diabetes: More than just one flavor? J. Endocrinol. Invest. 27:480. 9. De Silva, S., and Neuberger, J. (2006) HLA and autoimmune hepatitis. Liver Int. 26:509. 10. Selvaraj, P. (2000) Role of human leukocyte antigen (HLA) and non-HLA genes in susceptibility or resistance to pulmonary tuberculosis. Ind. J. Tub. 47:133. 11. Sing, N., Agrawal, S., and Rastogi, A.K. (1997) Infectious diseases and immunity: special reference to major histocompatibility complex. Emerging Infect. Dis. 3:41. 12. Shih, I.M. (2007) Application of human leukocyte antigen-G expression in the diagnosis of human cancer. Hum. Immunol. 68:272. 13. Chaudhuri, S., et al. (2000) Genetic susceptibility to breast cancer: HLA DQB*03032 and HLA DRB1*11 may represent protective alleles. Proc. Nat. Acad. Sci. USA 97:11451.

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