Next-generation sequencing

Maximize success in whole genome sequencing

Why choose whole genome sequencing?

Whole genome sequencing (WGS) allows researchers to profile the entire genome of interest and gain comprehensive insights into their samples. However, coverage issues, GC and amplification bias, as well as cumbersome workflows can make WGS expensive and time-consuming. We can help you navigate such obstacles with ease so that you can maximize success with WGS – regardless of your application.

Popular applications of WGS

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Scientist spotlight

Sequencing the world’s rarest coral

How do corals cope with climate change and accelerating warming temperatures? Dr. Bryan Wilson of the University of Oxford studies the resilience and recovery of coral reefs in an untouched part of the world in the central Indian Ocean. Discover how he unraveled this metagenomic jigsaw puzzle.

Read the story

Even genomic coverage offers insights into molecular endocrinology

Featured success story

Dr. Egbert Schulze from the Endocrinology and Nuclear Medicine Community Practice, Heidelberg, discusses how the all-enzymatic QIAseq FX workflow enabled uniform coverage and helped him achieve reliable sequencing results in his research.

Figuring out DNA fragmentation

DNA must be fragmented during whole genome sequencing library prep. What is the difference between enzymatic fragmentation, mechanical fragmentation and tagmentation? See the advantages and disadvantages of each.

Plan your experiment and implement it in your lab

Automated or manual library prep?

If your lab is processing hundreds or thousands of samples, manual library prep can slow down your insights. Manual handling errors and batch-to-batch inconsistency can add additional complications and impact on the accuracy of your results.

Discover library prep automation