References
1. Orth D, Grif K, Khan AB, Naim A, Dierich MP, Würzner R. The Shiga toxin genotype rather than the amount of Shiga toxin or the cytotoxicity of Shiga toxin in vitro correlates with the appearance of the hemolytic uremic syndrome. Diagn Microbiol Infect Dis. 2007;59(3):235-242. doi:10.1016/j.diagmicrobio.2007.04.013
2. Mühlen S, Dersch P. Treatment Strategies for Infections With Shiga Toxin-Producing Escherichia coli. Front Cell Infect Microbiol. 2020 May 6;10:169. doi: 10.3389/fcimb.2020.00169. PMID: 32435624; PMCID: PMC7218068.
3. European Centre for Disease Prevention and Control Annual Epidemiological Report 2021 – STEC https://www.ecdc.europa.eu/sites/default/files/documents/AER%20STEC%20-%202021.pdf. Accessed February 7, 2024
4. Den Ouden A, Greig DR, Rodwell EV, et al. Escherichia coli encoding Shiga toxin subtype Stx2f causing human infections in England, 2015-2022. J Med Microbiol. 2023;72(6):10.1099/jmm.0.001707. doi:10.1099/jmm.0.001707
5. Engberg J, Vejrum LK, Madsen TV, Nielsen XC. Verification of analytical bacterial spectrum of QIAstat-Dx® GI V2 and Novodiag® Bacterial GE+ V2-0 diagnostic panels. J Antimicrob Chemother. 2021;76(Suppl 3):iii50-iii57. doi:10.1093/jac/dkab242
6. Cointe A, Birgy A, Pascault A, et al. Be aware of Shiga-toxin 2f-producing Escherichia coli: case report and false-negative results with certain rapid molecular panels. Diagn Microbiol Infect Dis. 2020;98(4):115177. doi:10.1016/j.diagmicrobio.2020.115177|
6. From QIAstat-Dx Gastrointestinal Panel 2 (Cat. No. 691412) epidemiology dashboards in QIAsphere Insights, January 2023 – December 2023 for EMEA.*****
8. Johansen RL, Schouw CH, Madsen TV, Nielsen XC, Engberg J. Epidemiology of gastrointestinal infections: lessons learned from syndromic testing, Region Zealand, Denmark. Eur J Clin Microbiol Infect Dis. 2023 Sep;42(9):1091-1101. doi: 10.1007/s10096-023-04642-5. Epub 2023 Jul 19. PMID: 37468662; PMCID: PMC10427544. Study performed using QIAstat-Dx Gastrointestinal Panel (V1).
9. Rogers WS, Westblade LF, Soave R, et al. Impact of a Multiplexed Polymerase Chain Reaction Panel on Identifying Diarrheal Pathogens in Hematopoietic Cell Transplant Recipients. Clin Infect Dis. 2020;71(7):1693-1700. doi:10.1093/cid/ciz1068
*****These studies were conducted using QIAstat-Dx Gastrointestinal Panel 2 (Cat. No. 691412) or QIAstat-Dx Gastrointestinal Panel (V1). These CE-IVD products are not available in the U.S.
QIAsphere data from connected institutions were used for scientific research purposes only after applying proper de-identification procedures and anonymization techniques, in accordance with HIPAA and GDPR privacy and data protection rules. Data is aggregated from QIAsphere-connected QIAstat-Dx instruments only.
Unless otherwise indicated, data cited pertains to the use of a device from another manufacturer.