miRNA, microRNA, RISC, ribosome, mRNA, biogenesis, pre-miRNA, pri-miRNA, Exportin-5, Dicer, Argonaute, DGCR8, Drosha, gene expression, RNA, PCR
miRNA qPCR

miRCURY LNA miRNA Probe PCR

miRNA profiling is a critical process for measuring the expression levels of microRNAs (miRNAs), which play essential roles in gene regulation and various biological processes. To achieve accurate miRNA profiling, the use of high-quality miRNA primers is crucial. These primers are short sequences of nucleotides that provide the starting point for DNA synthesis during the PCR process, ensuring the specific amplification of miRNA targets.

Our miRCURY Probe PCR system is designed to provide exceptional sensitivity and specificity in miRNA profiling. Utilizing advanced miRNA primers guarantees reliable and reproducible results, even for low-abundance miRNAs. With our solutions, you can confidently perform miRNA profiling to uncover detailed insights into gene expression and regulation.

Robust and streamlined, the new miRCURY LNA miRNA Probe PCR system redefines miRNA profiling. miRNA quantification is extremely challenging. Their low abundance in common sample types often requires pre-amplification, and their short sequences make designing highly specific primers and probes difficult. The miRCURY LNA miRNA Probe PCR system addresses these issues, delivering robust, highly sensitive miRNA profiles for the most demanding applications. 

  • Unique combination of short, non-overlapping, fully miRNA-specific, LNA-enhanced primers and hydrolysis probe
  • Eliminates non-specific amplification and primer-dimer formation
  • Sensitive detection down to 1 copy without the need for pre-amplification
  • Fast and simple workflow – from RNA to data in just 2 hours
  • Accurate and highly discriminatory detection of any miRNA, regardless of sequence

Individual assays include LNA-enhanced primer/probe mix in tube format. Panels are available in 96- or 384-well formats for any real-time PCR cycler.

miRCURY Probe PCR Kits PCR mastermix designed for use with the miRCURY LNA miRNA Probe PCR system
miRCURY LNA miRNA Probe PCR Assays Over 30,000 predesigned assays covering all of miRBase 22
miRCURY LNA miRNA Custom Probe PCR Assays Custom-designed assays against novel miRNA targets
Available soon: miRCURY LNA miRNA Custom Probe PCR Panels Custom-designed, ready-to-use PCR panels containing predesigned and/or custom assays
Available soon: miRCURY LNA miRNA miRNome Probe PCR Panels Predesigned, ready-to-use PCR panels for human or mouse & rat miRNome profiling
Available soon: miRCURY LNA miRNA Focus Probe PCR Panels Predesigned, ready-to-use PCR panels focused on specific research areas or sample types

GeneGlobe helps you find and order predesigned miRCURY LNA miRNA Probe PCR Assays or create your own quickly and easily. But it’s so much more than an ordering platform. GeneGlobe links the most comprehensive assay portfolio – from PCR to NGS and functional analysis – to manually curated data on >10,000 biological entities, so you can explore targets in their scientific context and easily find the right tools for your research. User-friendly custom builders allow creation of custom products, and the embedded PCR and NGS analysis pipelines provide quick insights into your results and support planning of follow-up studies.

Watch the short intro video to learn more.