PICO technology from Actome detects proteins, protein interactions, and post-translational modifications of proteins. The PICO workflow is simple, enables parallel measurements and runs on QIAGEN's QIAcuity Digital PCR System.

PICO's advantages can best be illustrated by a striking new finding in the treatment of breast cancer. According to a recently published study on breast cancer treatment targeting HER2 overexpression, patients with low levels of HER2 expression may also benefit from anti-HER2 treatment, which demands better diagnostics. The latter, however, raises a question: how do we detect and quantify the low levels of HER2 required for these new applications? There is a limited amount of sample input material as well as a relatively low abundance of the target protein. How can we overcome these obstacles? In this webinar, we will show how PICO can help. But what if we ask further: what cellular functions are affected? How do cells react? It is likely that PICO holds the answers to these questions as well.