Human biomedical research, Microbiome, Foundation, Sample Technologies
Microbes and microbiome

Human Microbiome Research

Understanding microbiomes in the human body

The human body is a beautiful network of communication consisting of organs, tissues, cells and communities of microbes living in conjunction. The human microbiome can promote or deteriorate metabolic, mental or physiological health, and demystifying these microbial communities has become a priority in modern research. But human microbiome research is complex. Each environment in the body is unique, and material isolated from these samples sites should remain representative, regardless of the challenges presented by the bacteria, fungi, viruses or archaea contained within. This is why we have a dedicated microbiome team developing kits, research tools and assays that are sensitive, reliable and easy to use. Learn more about these and the microbiome researchers that use them below.

Smile like a Neanderthal

Could the ancient oral microbiome be the key to better overall health? According to Laura Weyrich, PhD, it might. Neanderthals had surprisingly good oral microbiomes. Now, she’s using this knowledge to gain insights into modern dental health. Read about the oral microbiome throughout history and her microbiome research journey here.

Find the specific product you need in an instant
Whether it be sample collection, RNA or DNA extraction, dPCR, NGS or digital data analysis, find the products specifically designed for your human microbiome studies with our interactive booklet
    
Which kit fits? Download our quick selection guide
Isolating microbial DNA, RNA or both? Need host DNA too? Get better results by matching your sample type and target with our tailored human microbiome kits even from small fecal samples.
Stool, swabs and saliva technical guidelines – expert advice for free

Stool, swabs and saliva technical guidelines – expert advice for free

Working with stool samples? What about microbial DNA or RNA from swabs or saliva? Our experts spill the tea with their best secrets and insider advice for isolating, preserving and analyzing human microbiome DNA and RNA in these technical guidelines. Download them now for free.

Can the gut microbiome alleviate cancer treatment side effects?

A person’s gut microbiota affects not only their overall health but also the effectiveness of certain therapies. Dr. Hannah Wardill researches human gut microbes with the goal of lowering the side effects that come with oncological patient care.

Hannah Rose Wardill
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All-in-one whole genome sequencing of the human microbiome

Metagenomics can describe the features of an environment in beautiful resolution, painting a picture of the community complexity. But microbial samples are complicated, challenging even experienced researchers. Furthermore, bias introduced through the methodology can blur the analytical details. This is why we have developed the QIAamp PowerFecal Pro WGS SeqSet, all-in-one bundles specifically designed to streamline the entire sequencing process, from nucleic acid extraction to library preparation to bioinformatics methods and statistical analysis.

All-in-one WGS –from isolation to analysis with one order
Understanding our world
Learn more about environmental and agricultural microbiome research.

FAQs about human biomedical microbiome research

What is the human microbiome?

Microorganisms (such as bacteria, archaea, fungi, viruses and eukaryotes) that live in communities on or in the human body are collectively called the human microbiome. These microbes, which live in a plethora of tissues, regions or fluids of the human body, can be beneficial or harmful depending on their composition.

What role does the human gut microbiome play in health and disease?

The gut microbiome plays a pivotal role in human health and disease and is essential for human development, immunity and nutrition. Often referred to as the microbiota-gut-brain-axis, the underlying molecular mechanisms that comprise the link between the gut microbiome and its effect on our brain and behaviour are slowly being revealed. The disturbance of the gut microbiome homeostasis has been associated with various pathological conditions, both systemic (obesity, diabetes, cancer and atopy) and gut-related (irritable bowel syndrome IBS, inflammatory bowel disease IBD).