Helping you unveil adaptive immune responses with an all-in-one solution
Accurate characterization of the T cell receptor (TCR) repertoire is key to understanding adaptive immune responses and has applications across vaccine development, autoimmunity, monitoring treatment response in lymphoid malignancies and immunotherapy. Compared to traditional methods, next-generation sequencing (NGS) provides an unprecedented, high-resolution picture of the immune repertoire. However, the complex workflows and high time investment required can make developing automated NGS workflows challenging. In addition, this approach involves multiplex PCR with primers targeting different V or J regions, which can introduce substantial amplification bias.
QIAGEN Genomic Services has risen to meet these challenges with our convenient, all-in-one Immune Repertoire Profiling Services. Extend your in-house resources with the expertise, powerful bioinformatics and custom services that you expect from QIAGEN. Using our proven sample preparation and targeted NGS technologies, we deliver end-to-end expertise to support your adaptive immune response studies. Our profiling solution offers the following benefits:
- End-to-end service: We take care of every step, from sample preparation to data analysis
- Guidance and flexibility: We aid in designing your project and help you make the right decisions
- Optimized TCR variable region enrichment: We use unique molecular indices to reduce amplification bias, providing accurate and sensitive clonotype and repertoire diversity assessment
- Ready-to-publish data: We deliver comprehensive reports and data packages, and provide guidance on the next steps
