What is the DNA integrity from PAXgene Tissue fixed, paraffin-embedded (PFPE) tissue?
In contrast to DNA isolated from formalin-fixed, paraffin-embedded (FFPE) tissue, DNA from PFPE tissue exhibits high molecular weight. In most cases, a distinct 10 kb band is observed with agarose gel electrophoresis. For an example, see Figure 2 in the technical note “Quantitative analysis of KRAS and BRAF mutational status in DNA from PAXgene Tissue fixed, paraffin-embedded (PFPE) tissue using Pyrosequencing technology“.