What is the maximum size of tissue that can be fixed in a PAXgene Tissue FIX Container (50 ml)?

Up to 4 standard tissue cassettes, each containing tissue samples with a maximum size of 4 x 15 x15 mm, can be placed into a PAXgene Tissue FIX Container (50 ml). Alternatively, a single tissue sample with a maximum size of 20 x 20 x 20 mm can be directly fixed in a PAXgene Tissue FIX Container (50 ml). If using a larger tissue sample with a maximum size of 20 x 20 x 20 mm surrounded by fat (e.g., from a lymph node) or capsule (e.g., from kidney, liver, or spleen tissue), partially cut into the tissue every 5 mm (lamination) to enhance permeability of the fixative reagent.