3233 - Is the yield and quality of RNA and DNA purified with the AllPrep DNA/RNA FFPE Kit comparable to yield and quality of nucleic acids purified separately with other methods.
Yes, gained yields and quality are comparable. Separation of RNA from DNA in the AllPrep protocol is highly effective. As A260 values measure both DNA and RNA, lower A260 values from DNA purified using the AllPrep DNA/RNA FFPE Kit may indicate high DNA purity and the absence of contaminating RNA. Higher A260 values from DNA purified using alternative methods may indicate the presence of significant amounts of contaminating RNA.