QIAstat-Dx Rise

For higher throughput multiplex syndromic testing applications

S_1272_6_MDx_ST_QIAstat_Dx
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QIAstat-Dx Analytical Module

Cat. No. / ID:   9002814

Module contains the hardware and software for sample testing and analysis
InstrumentPanel
QIAstat-Dx Analytical Module
QIAstat-Dx Respiratory SARS-CoV-2 Panel
QIAstat-Dx Gastrointestinal Panel 2
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Features

  • Uses real-time PCR to deliver comprehensive results for up to 160 patient samples per day with 8 Analytical Modules
  • Easily view Ct values and amplification curves for all detected pathogens
  • Single-step cartridge preparation with no precision pipetting required and unique direct swab protocol
  • Load the full capacity of cartridges in just a few minutes and safely dispose of all used cartridges from the waste tray in one quick step

 

 

Product Details

QIAstat-Dx simplifies infectious disease diagnostics so you can get faster results for your patients. All you need are a patient sample, a QIAstat-Dx assay cartridge and one of our intuitive QIAstat-Dx instruments. 


QIAstat-Dx Rise is our higher-throughput powerhouse, built to fit the needs of high-demand institutions. Combined with QIAstat-Dx assay cartridges, QIAstat-Dx Rise uses multiplex PCR technology – also known as syndromic testing – to quickly survey many different pathogens in a single patient sample. The cartridges come ready with all reagents preloaded and use our trusted assay chemistry. The system includes random access and batch testing options, with a daily capacity of 160 samples using 8 Analytical Modules. The QIAstat-Dx Rise also includes a multi-test front drawer that can accommodate up to 18 cartridges at the same time, and a waste drawer to automatically collect used cartridges.


Each instrument is made up of two components: 1) A QIAstat-Dx Rise Base, which contains the intuitive touch-screen interface and robotic system that moves and scans the cartridges within the device and 2) Between 1 through 8 Analytical Modules, letting you test up to eight samples at once. 

With QIAstat-Dx Rise in your lab, you can: 

  • Gain time away from your instruments: Batch process up to 16 cartridges using 8 Analytical modules.
  • Process priority tests fast: Get random access through 2 additional urgent testing slots. 
  • Load and go: Load the full capacity of cartridges in just a few minutes and safely dispose of used tests in one step.

Plus, every QIAstat-Dx Analytical Module is compatible with both QIAstat-Dx Analyzer 2.0 and QIAstat-Dx Rise. Easily update your QIAstat-Dx testing format based on your evolving testing needs. Click here to more about QIAstat-Dx Analyzer 2.0, our modular system perfect for labs of every size.

 

Principle

QIAstat-Dx Rise, combined with QIAstat-Dx assay cartridges, uses real-time PCR to detect pathogen nucleic acids in human biological samples. The instrument and cartridges are designed as a closed system that contain on board all necessary reagents, enabling hands-off sample preparation. Detected real-time amplification signals are interpreted by the integrated software and are reported via an intuitive user interface.

Procedure

Preparing a QIAstat-Dx cartridge using liquid transfer or dry swab sample application is efficient and fast. And once the cartridges are ready, it takes just a few minutes to load the full capacity of cartridges and start a run on QIAstat-Dx Rise. 

Loading a sample into the QIAstat-Dx cartridge requires less than one minute hands-on time with no precision pipetting.

Using the provided transfer pipette, the user applies a liquid sample to the main port of the QIAstat-Dx cartridge (see  Applying a liquid sample to the QIAstat-Dx cartridge). Alternatively for our respiratory assay, a dry swab sample may be directly applied to the cartridge ( Applying a dry swab to the QIAstat-Dx cartridge).

Following the instructions on the QIAstat-Dx Rise touchscreen display, the user loads the prepared cartridges into the instrument’s loading tray (see  Adding cartridges to the QIAstat-Dx Rise input tray).

The QIAstat-Dx Rise will automatically scan the sample ID and cartridge barcodes, or the user can manually scan the barcodes. Once the user starts the run, the QIAstat-Dx Rise will autonomously process the samples. 

The input tray also offers random and continuous access, meaning an urgent test can be added to an ongoing run at a moment’s notice. 

Once the run is finished, the used cartridges are automatically placed in the dedicated waste tray so they can be disposed of safely and quickly.

 

See figures

Applications

QIAstat-Dx Respiratory SARS-CoV-2 Panel (V2): Qualitative test to analyze 23 viral and bacterial respiratory targets for common pathogens causing respiratory infections, including SARS-CoV-2.

 

QIAstat-Dx Respiratory SARS-CoV-2 Panel (V2) – 23 bacterial and viral pathogens
Viruses   Bacteria
Influenza A Parainfluenza virus 1  
Influenza A subtype H1N1/2009 Parainfluenza virus 2  
Influenza A subtype H1 Parainfluenza virus 3  
Influenza A subtype H3 Parainfluenza virus 4 Mycoplasma pneumoniae
Influenza B Respiratory syncytial virus A/B Legionella pneumophilia
Coronavirus 229E Human metapneumovirus A/B Bordetella pertussis
Coronavirus HKU1 Adenovirus Chlamydophila pneumoniae
Coronavirus NL63 Bocavirus  
Coronavirus OC43 Rhinovirus/Enterovirus*  
SARS-CoV-2    

*Enterovirus and Rhinovirus are both detected, but not differentiated, with the QIAstat-Dx Respiratory SARS-CoV-2 Panel.

The QIAstat-Dx Respiratory SARS-CoV-Panel (V2) is currently available in select countries.

 

QIAstat-Dx Gastrointestinal Panel 2: Qualitative test to analyze 22 of the most common pathogens causing gastrointestinal infections, including differentiation of Shiga-like toxin producing E. coli (STEC) stx1 and stx2.

QIAstat-Dx Gastrointestinal Panel 2 – 23 targets, corresponding to 22 bacterial, viral and parasitic pathogens
Bacteria   Viruses Parasites
Campylobacter (C. jejuni, C. upsaliensis, C. coli) Salmonella spp. Adenovirus F40/41 Cryptosporidium
Clostridium difficile (toxin A/B) Shiga-like toxin-producing E. coli (STEC) stx1 and stx2 (including specific identification of E. coli O157 serogroup within STEC)** Astrovirus Cyclospora cayetanensis
Enteroaggregative E. coli (EAEC) Vibrio vulnificus Norovirus (GI, GII) Entamoeba histolytica
Shigella/Enteroinvasive E. coli (EIEC) Vibrio parahaemolyticus Rotavirus A Giardia lamblia
Enteropathogenic E. coli (EPEC) Vibrio cholerae Sapovirus (GI, GII, GIV, GV)  
Enterotoxigenic E. coli (ETEC) lt/st Yersinia enterocolitica    
Plesiomonas shigelloides      

**The stx1 and stx2 toxin genes of STEC are reported separately by the QIAstat-Dx Gastrointestinal Panel 2.

 

Features Specifications
Configuration Modular syndromic testing system with QIAstat-Dx Rise Base, up to 8 QIAstat-Dx Analytical Modules and 1 QIAstat-Dx Rise Mobile Table (optional).
Instrument dimensions (WxHxD) QIAstat-Dx Rise Base (door closed): 580 x 1280 x 810 mm (22.8 x 50.4 x 31.9 in) 
QIAstat-Dx Rise Base (door open): 1500 mm x 1280 x 810 mm (59 x 50.4 x 31.9 in)
For installation and service interventions, 1.5 m of space around the instrument is required.
Weight QIAstat-Dx Rise Base: 130 kg
QIAstat-Dx Analytical Module: 16 kg
QIAstat-Dx Rise Mobile Table (load-bearing capacity): 300 kg
Power requirements 200–240 VAC
Recommended clearance Left side: 80 cm
Top: 32 cm
Front: 140 cm
Operating conditions Specifications
Air temperature 15–28 ̊C
Relative humidity 20–80%
Altitude 0–2200 m
Place of operation Laboratory (inside)

 

Supporting data and figures

Resources

Operating Software (1)
For use with the QIAstat-Dx Analyzer and the DiagCORE Analyzer
Safety Data Sheets (1)
Software User Guides (2)
Certificates of Analysis (1)