OEM by QIAGEN offers bulk manufacturing of T4 RNA Ligase 1 in custom formulations.

For collection of whole blood samples and stabilization of circulating cell-free DNA (ccfDNA) from plasma and genomic DNA (gDNA) from the nucleated cellular fraction

For the ligation of single-stranded or double-stranded RNA molecules, as well as RNA-DNA hybrids

For the ligation of RNA molecules, facilitating the joining of RNA fragments or the addition of RNA adapters

For joining or ligation of DNA fragments, particularly in DNA sequencing and cloning techniques

For dye-based one-step RT-PCR on the QIAcuity digital PCR instruments

For in vitro transcription and synthesizing RNA from a DNA template

For the hands-free isolation of DNA from soil and stool using your automation workflow of choice

For multiplex amplification of all Chinese National database loci and CODIS-required markers with an innovative Quality Sensor

For efficient digestion of proteins in biological samples and for eliminating DNases and RNases during nucleic acid isolation

Comprehensive oncology profiling combining gene fusion detection, gene expression analysis and single nucleotide variant (SNV) calling in just one assay

Comprehensive oncology profiling combining gene fusion detection, gene expression analysis and single nucleotide variant (SNV) calling in just one assay

For preparing libraries from unidentified persons and remains samples

For rapid rRNA removal for RNA-seq library preparation from Caenorhabditis elegans (worm) samples

For rapid rRNA removal for RNA-seq library preparation from fish total RNA samples

For rapid rRNA removal for RNA-seq library preparation from Drosophila melanogaster (fly) samples

To support customers developing in-house assays using real-time PCR molecular testing

OEM by QIAGEN offers bulk manufacturing of ER/A-Tailing Enzyme Mix in custom formulations.

For the detection of PAMG-1 in amniotic fluid found in vaginal discharge of pregnant women

For the detection of PAMG-1 in amniotic fluid found in vaginal discharge of pregnant women

Urine collection and cell-free DNA stabilization from urine liquid biopsy samples

For targeted viral and bacterial sequencing using hybrid capture

For highly sensitive and specific one-step and multiplex qRT-PCR

For use in normalizing your relative gene expression profiling experiment

For quantification of DNA or cDNA targets in singleplex or multiplex digital PCR (dPCR) using the QIAcuityDx System

For protease digestion during DNA and RNA preparation

For automated purification of ccfDNA from 1–192 samples using the QIAsymphony SP

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In this webinar, we will take a look at a large-scale SNP-based forensic identification panel for DNA analysis with massively parallel sequencing (MPS). The panel was specifically designed for the challenges of identifying missing persons; where DNA is frequently highly degraded, and relationship tests may involve reference samples from across several generations and in a deficient pedigree.

The FBI CODIS Core Loci Working Group have published the recommendation that the CODIS core loci should be expanded, and a combination of STR markers from the Combined DNA Index System (CODIS), the European Network of Forensic Science Institutes (ENFSI), and the European DNA Profiling Group (EDNAP) should be used to improve the accuaracy of forensic testing. QIAGEN has developed new kits — Investigator 24plex Kits — that coamplify all 23 recommended markers. The kits use novel 6-dye technology to keep the amplicon length of markers short while avoiding overlapping of markers. Kits are available for purified DNA from casework and for reference samples. This webinar will outline the benefits of the Investigator 24plex Kits and highlight the improved workflow, which saves unnecessary re-runs of a sample by use of an internal “Quality Sensor” control. This unique Quality Sensor can distinguish: Successful amplification Degraded DNA Inhibited DNA No DNA Failed PCR amplification Join us to learn how to improve results and streamline your forensic STR analysis with the new Investigator 24plex Kits.

The core short tandem repeats (STRs) in worldwide use have served the forensic analyst very well for many years. Further, recent expansions of European Standard STR sets plus ongoing discussions to extend CODIS have brought powerful upgrades to the battery of core markers available. However, there are still scenarios when supplementary STRs could enhance the data necessary for interpreting complex forensic patterns: making safer inferences about relatedness across distant relationships in deficient pedigrees, and in the not too distant future, improving the specificity of familial searching or expanding the points of reference to better interpret mixed profiles. The QIAGEN HDplex Kit contains 9 completely novel STRs in addition to ESS or CODIS D12S39, D18S51 and SE33 markers. On an average, these 9 novel STRs provide higher powers of discrimination than kits using the core loci alone. This webinar will outline the completed studies on worldwide patterns of variability in the 12 novel HDplex STRs and their ability to enhance the power of paternity analyses when combined with existing markers. It will also describe the upgraded pop.STR allele frequency browser which provides data for 23 core STRs plus a total of 28 supplementary STRs in 56 global populations. Join us to learn more on: Enhancing data necessary for interpreting complex forensic patterns with supplementary STRs Making safer inferences about relatedness across distant relationships in deficient pedigrees Improving the specificity of familial searching to better interpret mixed profiles

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