ipsogen JAK2 MutaSearch Kit CE

• Highly sensitive and accurate qualitative assay
• Improved level of detection with 1% clinical positivity cut-off
• Compliance with EU IVD Directive 98/79/EC
• Easy workflow with ready-to-use solutions

To ensure highest sensitivity, the ipsogen JAK2 MutaSearch Kit has been optimized to detect the JAK2 V617F/G1849T mutation and uses a DNA cut-off sample with 1% (COS) positivity and DNA positive and negative controls for qualitative analysis (see figures  Accurate detection of JAK2 V617F mutation, 1% cut-off sample, and positive and negative controls and  Reliable detection of wild-type JAK2, 1% cut-off sample, and positive and negative controls). A minimum of 25 ng of input sample DNA is recommended.

The ipsogen JAK2 MutaSearch Kit is a ready-to-use kit for the detection and qualitative analysis of the JAK2 V617F/G1849T somatic mutation due to a single nucleotide polymorphism (SNP) in genomic DNA extracted from peripheral blood of subjects with suspected myeloproliferative neoplasm (MPN) (see figure  JAK2 mutation site identification). The kit provides high levels of sensitivity and reproducibility. The ipsogen JAK2 MutaSearch Kit provides a DNA cut-off sample (COS), a positive control (PC), and a negative control (NC) for JAK2 V617F. Use of the cut-off sample and controls enables accurate qualitative analysis of genotyping results.