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Syndromic testing

Better therapeutic precision for respiratory symptoms

1 instrument. 2 FDA-cleared panels. Better individual care.

Antibiotics for viral respiratory infections? It seems counterintuitive. But it's surprisingly common – and a big driver of antibiotic resistance.

Practicing good antimicrobial stewardship starts with a diagnosis. But not every test is right for every patient. That's why we offer two FDA-cleared respiratory panels:

QIAstat-Dx Respiratory Panel Plus: For high-risk patients. This extended panel tests for 18 viruses and 3 bacteria, giving you comprehensive coverage of circulating pathogens.

QIAstat-Dx Respiratory Panel Mini: For low-risk patients. Hone in on the five most prevalent respiratory viruses.

With just one instrument and two FDA-cleared tests, you can fine-tune your diagnostic approach and provide better individual care.

Comprehensive answers for your high-risk patients

Respiratory illnesses can be particularly dangerous for high-risk individuals, such as those with comorbidities. Diagnosing these infections quickly is crucial but often challenging, leading to a delay in appropriate treatment.

Imagine being able to test for 18 viruses and 3 bacteria in just about an hour. That's exactly what QIAstat-Dx can do.

1 panel. 21 targets. ~1 hour.

With results for 21 viral and bacterial targets in about an hour, the QIAstat-Dx Respiratory Panel Plus can help you improve triage and infection control for your most vulnerable patients. And provide better care, faster.

Targeted answers for your low-risk patients

Respiratory illness tops the list for outpatient visits, but not every cough or sneeze needs antibiotics.

Now you can get the right answer fast with our FDA-cleared QIAstat-Dx Respiratory Panel Mini. Hone in on the five most prevalent respiratory viruses in about an hour to make more precise treatment decisions.

Let's chat about how we can improve your respiratory testing
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Get additional insight with cycle threshold (Ct) values

Need help navigating the complex landscape of respiratory illness? Are overlapping symptoms and confusing co-detections acting as road bocks to diagnosis?

Cycle threshold (Ct) values from QIAstat-Dx syndromic testing can give you added insights to aid in clinical interpretation.

Read on to learn how QIAstat-Dx Ct values can support you.

Don't settle for a partial pictures of co-infections

Respiratory co-infections are far from rare and can worsen symptoms (1). A recent study showed that co-detections involving two pathogens occur 12.4% of the time (2). Co-detections involving three or even four respiratory pathogens are also possible (2).

Comprehensive syndromic testing is crucial, but additional information may be necessary for clinical interpretation.

In these cases, Ct values can help. And that's where QIAstat-Dx stands out, uniquely providing easy access to Ct values and amplification curves for enhanced clinical insights.

Percentage of total respiratory detections involving two, three or four co-detected pathogens. Adapted from (2).
Percentage of total respiratory detections involving two, three or four co-detected pathogens. Adapted from (2).
I think that [Ct values] can help in the interpretation of the results, in particular in case of co-infections, in order to understand what is the virus or the bacteria that is probably more correlated with the clinical problem.
Liliana Gabrielli, MD, Microbiology Unit, IRCCS Azienda Ospedaliero-Universitaria of Bologna, Policlinico di Sant'Orsola, Italy

Case study: Seeing beyond the respiratory symptoms with Ct values

A real clinical case resolved with results from QIAstat-Dx, provided by Xiaohui Nielsen, MD, PhD, Department of Clinical Microbiology, Zealand University Hospital, Denmark.

  • A 1-year-old child with a four-day history of fever, cough and runny nose was admitted after experiencing progressive difficulty breathing
  • QIAstat-Dx* results came back quickly as positive for: Parainfluenza virus 3 (Ct: 19); Rhinovirus/enterovirus (Ct: 32); Adenovirus (Ct: 34)
  • Outcome: With a low Ct value of 19, parainfluenza virus 3 was suggested as the etiological agent of respiratory illness, while rhinovirus/enterovirus and adenovirus were correlated with co-infection. The child recovered and was discharged after three days.
  • Ct values can add an extra layer of information to aid in clinical diagnosis and help you determine the etiology of a respiratory syndrome.
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Webinar: How the right respiratory test can impact antimicrobial stewardship

How can clinicians improve diagnostic accuracy for respiratory illness? And how can this impact antimicrobial stewardship? Watch our on-demand webinar with resident expert Neil Grossman to find out.

Neil Grossman Webinar On-demand cover
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Get to know QIAstat-Dx

QIAstat-Dx simplifies infectious disease diagnostics so you can get faster results for your patients. All you need are a patient sample, a QIAstat-Dx assay cartridge and the intuitive QIAstat-Dx Analyzer 1.0 or 2.0.

  • Get answers fast: Results for several pathogens in about an hour.
  • Additional insights: See Ct values and amplification curves for additional insight on co-detections.
  • Fully customizable: Equip it with between one to four Analytical Modules to test up to four samples at once.
  • Save space: A small benchtop unit you can fit in any corner of your lab.
  • Stay connected: Real-time test updates and custom epidemiology reports through QIAsphere.**

References

  1. Liu Y, Ling L, Wong SH, et al. Outcomes of respiratory viral-bacterial co-infection in adult hospitalized patients. EClinicalMedicine. 2021;37:100955. Published 2021 Jun 10. doi:10.1016/j.eclinm.2021.100955
  2. Ali U, Zainal M, Zainol Z, et al. Performance evaluation of two multiplex qualitative RT-PCR assays for detection of respiratory infection in pediatric population. Malays J Pathol. 2023;45(2):215-227.

* This case was resolved using the QIAstat-Dx Respiratory SARS-CoV-2 Panel (Cat. No. 691214). This version of the panel is not available in the U.S. or Canada.
** Some features require a QIAstat-Dx Connectivity plan. Flexible plans are available to meet your needs.

For up-to-date licensing information and product-specific disclaimers, see the respective QIAGEN kit instructions for use or user manual. QIAGEN instructions for use and user manuals are available at www.qiagen.com or can be requested from QIAGEN Technical Services (or your local distributor).