The digene HPV Test (digene HC2 High-Risk HPV DNA Test and digene HC2 HPV DNA Test) has been approved in Europe and the United States since 1999. More than 300 peer-reviewed journal articles have data generated with the digene HC2 High-Risk HPV DNA Test, and the test has been studied in international clinical trials involving over 1 million women worldwide. The digene HPV Test is the world's most proven HPV test for sensitive, early detection of cervical cancer and disease. The digene HC2 High-Risk HPV DNA Test is CE-marked for testing for high-risk types of HPV.