Circulating tumor cells (CTCs) are rare and highly heterogeneous. In addition, during the epithelial-mesenchymal transition (EMT) process, CTCs lose their epithelial characteristics and acquire more mesenchymal-like phenotypes, which pose another challenge for CTC detection and characterization. In this slidedeck, Dr. Siegfried Hauch introduces the AdnaTests, which use the Combination of Combinations Principle (COCP) to enable enriching and detecting CTCs in whole blood with high specificity and sensitivity.
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